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Tibolone


Tibolone Brands
Brand Name Manufacturer Name Distributor Drug Strength Packaging Formulation Formulation Strength Price
Livial Organon Pharma (see Schering plough) C.Mehta & Co Ltd. 2.5mg 28 Tablet per tablet KES 2,508.00
Tibon Questa Care Inc. Simba Pharmaceutical Ltd. 2.5mg 28 Tablet per tablet KES 1,300.00
Tibolone More info
Mode Of Action

Tibolone possesses estrogenic, progestogenic and androgenic activities

Drug Indication Vasomotor symptoms following menopause (natural or surgical). (It shows minimal risks of endometrial hyperplasia or neoplasia as compared to oestrogen).
Precautions Renal / hepatic impairment; signs of thrombo-embolic diseases; diabetes mellitus; epilepsy; migraine; and hypercholesterolaemia
Contra-Indications Unexplained vaginal bleeding; pregnancy and lactation; hormonal dependent tumours; severe hepatic impairment; cerebral vascular disease (history or current); cardiovascular disease (history or current).
Side Effects Vaginal bleeding; GI disturbances; ankle edema; weight changes; dizziness; allergic reactions; increased facial hair; migraine; liver function changes.
Dosage 2.5mg daily
Pregnancy Category Category D
Pregnancy Category Description Drugs, which have caused, are suspected to have caused, or may be expected to cause an increased rise in the frequency of malformations or irreversible damage. These drugs may also have adverse pharmacological effects required required